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Maternal glucose response to a standardized test meal throughout pregnancy and postnatally
D M Campbell1, H W Sutherland, D W Pearson
1University of Aberdeen, Foresterhill, Scotland.
Objective:
Our purpose was to determine the maternal blood glucose response to food throughout pregnancy.
Study Design:
Forty-five normal, healthy primiparous women with singleton pregnancies were studied longitudinally throughout pregnancy. Blood glucose levels were determined at each stage of pregnancy after a standardized test meal.
Results:
Fasting plasma glucose decreased throughout gestation and rose again significantly post partum. Glucose values at 30, 60, 90, and 120 minutes after a standardized test meal were similar at all gestational ages studied.
Conclusions:
Plasma glucose levels after a physiologic challenge with food do not alter with advancing gestation. This has implications both for the management of insulin-dependent diabetes during pregnancy and for the diagnosis of gestational diabetes.
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