[Haptoglobin phenotypes and biochemical parameters of blood serum]

Haptoglobin (Hp) phenotypes were determined in 646 subjects aged 25 to 76. Hp phenotype distribution in the examinees (13.6% for type 1-1; 49.4% for type 2-1; and 37.0% for type 2-2) was found as expected. Levels of eighteen metabolic, enzymatic, hormonal, and immunologic blood serum parameters were studied in subjects with various Hp phenotypes. Elevated levels of uric acid (by 12%, p < 0.01) and lactate dehydrogenase activity (by 7%, p < 0.05) in Hp 1-1 type were revealed as against other Hp types. A higher uric acid level in Hp 1-1 type was found in subjects of different age and both sexes, whereas LDH activity elevation was observed only in men aged over 55.