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[Malignant solid tumors in the first year of life]
A Roguin1, M W Ben-Arush, G Renart
1Pediatric Oncology Unit, Rambam Medical Center, Haifa.
Harefuah
|May 15, 1994
Summary
Pediatric malignant solid tumors are rare in Northern Israel, with neuroblastoma being the most common. Incidence varied by sex, ethnicity, and Jewish subgroup.
Area of Science:
- Pediatric Oncology
- Epidemiology
Context:
- Analysis of malignant solid tumors in children under 1 year in Northern Israel from 1973-1990.
- Identified 64 cases (39 boys, 25 girls).
Purpose:
- To determine the incidence and types of malignant solid tumors in infants in Northern Israel.
- To investigate demographic and ethnic variations in pediatric cancer incidence.
Summary:
- Overall annual incidence was 137.1 per million.
- Higher incidence in boys, Jews vs. non-Jews, and Ashkenazic vs. Sephardic Jews.
- Neuroblastoma was most common (52%), followed by Wilms' tumor (13%) and CNS neoplasms (11%).
- Retinoblastomas occurred exclusively in non-Jews, while Jews had a higher neuroblastoma incidence.
Impact:
- Provides crucial epidemiological data on pediatric cancers in a specific region.
- Highlights ethnic and demographic disparities in cancer incidence.
- Informs targeted public health strategies and future research in pediatric oncology.