Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Worldwide measles prevention

W A Orenstein1, L E Markowitz, W L Atkinson

  • 1Division of Immunization, Centers for Disease Control and Prevention, Atlanta, GA 30333.

Israel Journal of Medical Sciences
|May 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Human papillomavirus (HPV) types among Alaska native women attending a colposcopy clinic in Anchorage, Alaska, 2009-2011.

Infectious agents and cancer·2020
Same author

Development and acceptability of a video-based vaccine promotion tutorial for obstetric care providers.

Vaccine·2019
Same author

Assessing population immunity for measles elimination - The promise and peril of serosurveys.

Vaccine·2018
Same author

Measles and Rubella Global Strategic Plan 2012-2020 midterm review.

Vaccine·2018
Same author

Improving influenza and Tdap vaccination during pregnancy: A cluster-randomized trial of a multi-component antenatal vaccine promotion package in late influenza season.

Vaccine·2015
Same author

A probability model for evaluating the bias and precision of influenza vaccine effectiveness estimates from case-control studies.

Epidemiology and infection·2014
Same journal

Coronary revascularization versus conservative medical management for preoperative optimization of a patients with documented ischemic heart disease.

Israel journal of medical sciences·1998
Same journal

Primary biliary cirrhosis--association or overlap with other autoimmune diseases.

Israel journal of medical sciences·1998
Same journal

Complementary medicine--the problem and the challenge.

Israel journal of medical sciences·1998
Same journal

Electroencephalography in the evaluation of headache patients: a review.

Israel journal of medical sciences·1998
Same journal

Complementary medicine--a critical review.

Israel journal of medical sciences·1998
Same journal

The Israel Longitudinal Mortality Study--differential mortality in Israel 1983-1992: objectives, materials, methods and preliminary results.

Israel journal of medical sciences·1998
See all related articles

Measles vaccination significantly reduced deaths, but a single dose is insufficient for elimination. Improved control strategies, including two-dose schedules, are vital to prevent ongoing global measles mortality.

Area of Science:

  • Virology
  • Immunology
  • Public Health

Background:

  • Measles caused over 2.5 million annual deaths before vaccine introduction.
  • Epidemiology of measles differs between developed and developing countries, impacting disease burden in different age groups.
  • Current single-dose measles vaccination strategies face challenges in timely infant immunization and disease elimination.

Purpose of the Study:

  • To analyze the effectiveness and limitations of current measles vaccination strategies.
  • To explore potential improvements in measles vaccine efficacy and delivery for infants.
  • To discuss the necessity of enhanced control measures for measles prevention.

Main Methods:

  • Review of historical measles mortality data.
  • Analysis of measles epidemiology in diverse global settings.

Related Experiment Videos

  • Evaluation of single-dose versus two-dose vaccination schedules.
  • Assessment of high-potency vaccine efficacy and safety concerns.

    • Main Results:

    • Single-dose measles vaccination (Schwarz strain) at 9 months with 80% coverage has saved over 1.6 million lives.
    • High-potency vaccines show potential for infant immunization but raise safety questions.
    • Standard vaccines reduce incidence but do not prevent outbreaks in unvaccinated populations, necessitating two-dose schedules in many developed nations.

    Conclusions:

    • Measles immunization has drastically reduced disease occurrence but has not eliminated it.
    • A single vaccine dose controls measles but is inadequate for eradication.
    • Enhanced control strategies, potentially including two-dose schedules, are crucial to prevent the estimated 1 million annual deaths.