Pityriasis rosea-like eruption after bone marrow transplantation

Area of Science:

• Dermatology
• Hematology
• Immunology

Background:

• Bone marrow transplantation (BMT) is linked to various cutaneous complications.
• These skin issues can stem from the underlying disease, conditioning regimens, immunosuppression, medications, or graft-versus-host disease.

Observation:

• Four bone marrow transplant recipients presented with clinical and histologic findings consistent with pityriasis rosea.
• Pityriasis rosea is a common, self-limiting skin condition typically characterized by a herald patch followed by a generalized rash.

Findings:

• This case series describes a previously unreported association between bone marrow transplantation and pityriasis rosea.
• The development of pityriasis rosea in these patients suggests a potential link to the BMT process or its complications.

Implications:

• Further research is needed to elucidate the mechanisms underlying this association.
• Recognizing pityriasis rosea as a potential complication of BMT may aid in timely diagnosis and management.
• This finding expands the spectrum of known cutaneous complications following bone marrow transplantation.