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[Renal botryomycosis. Clinicopathologic study of a case]
A François1, J L Bacri, J Métayer
1Service d'Anatomie et Cytologie Pathologiques A, CHU de Rouen.
Annales De Pathologie
|January 1, 1994
Summary
Botryomycosis, a chronic bacterial infection, can present in the kidney. This case highlights Escherichia coli as a rare cause of renal botryomycosis, confirmed by histological and immunohistologic findings.
Area of Science:
- Medical Microbiology
- Pathology
- Nephrology
Background:
- Botryomycosis is a chronic bacterial infection characterized by granules containing bacteria within microabscesses.
- Staphylococcus aureus is the most frequent pathogen, but other bacteria can also cause this condition.
- Pathogenesis theories involve foreign bodies, bacterial load/virulence, and host immune status.
Observation:
- A 60-year-old woman presented with clinical signs of a urinary tract infection.
- Diagnostic workup revealed Escherichia coli as the causative agent.
- Histological examination showed characteristic granules, and immunohistology confirmed the presence of anti-Escherichia coli antibodies within these granules.
Findings:
- This report details the seventh documented case of renal botryomycosis.
- Escherichia coli was identified as the specific bacterial agent responsible for the renal infection.
- The diagnosis was corroborated by a combination of clinical, histological, and immunohistologic evidence.
Implications:
- This case expands the known spectrum of bacterial pathogens implicated in renal botryomycosis.
- It underscores the importance of considering less common etiologies in chronic urinary tract infections with unusual histological findings.
- Further research into the pathogenesis of botryomycosis caused by Gram-negative bacteria like Escherichia coli is warranted.