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Synthesis, Characterization, and Application of Superparamagnetic Iron Oxide Nanoprobes for Extrapulmonary Tuberculosis Detection
Published on: February 16, 2020
[Yield of active search of tuberculosis in a marginal population]
J M Jiménez Luque1, E Herrera Morcillo, N Lora Cerezo
1Unidad Docente de Medicina Familiar y Comunitaria, Centro de Salud Occidente, Córdoba.
Objectives:
A prevalence study on tuberculosis infection among school-children in our area. A study of the family, contacts and teachers of infected children. An analysis of the level of compliance with diagnostic and therapeutic procedures.
Design:
Observational and descriptive. Clinical-epidemiological.
Setting:
An urban Basic Health Area with 18,000 inhabitants.
Patients And Other Participants:
393 people were included in the study: 162 school-children doing first-year EGB [c. six years old], 199 family members and contacts of the infected children and 32 EGB teachers.
Measurements And Main Results:
Mantoux intradermoreaction. Application of the study procedure. Following of the evolution and monitoring of the treatment. We found 6 infected children (3.7% of the school-children), all of whom came from the same marginalised area. Among the 231 family members, contacts and teachers studied, we found 30 cases of active Tuberculosis (13%) and 71 cases of infection (30.7%). Antituberculous treatment was indicated for all cases of illness and secondary Chemoprophylaxis for 49 cases. The study could not be completed in 62 cases.
Conclusions:
The prevalence of tuberculous infection among school-children from the marginalised area is high. Examination of the infected childrens' contacts showed a high level of tuberculous infection. Follow-up of the diagnostic and therapeutic procedures was incomplete for a significant percentage of those under study.
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