[The sesquiterpene lactone "azerin" has memory enhancing properties]

The memory property of Sesquiterpene Lactone Azerin, isolated from the plant species Ferula compared with placebo (PCO) and clinical well known drug Nootropyl/Piracetam (NOO) were studied on rats. The experiments showed that Azerin in 7-8 times improved the ability of rats to keep the signs of Passive Avoidance Response (PAR), when NOO only in 3-4 times. The learning and transcorneally amnesic electro-shock leaded to 100% PCO, 63% NOO and only 20% Azerin rats retrograde amnesia syndrome. Thus, the mechanisms of amnestic and antiamnestic properties of Azerin have been studied.