[Clinical polymorphism of neoplastic and vascular brain diseases: pathogenetic characteristics]

Using evidence on 533 patients with an atypical course of brain tumors and vascular diseases, the author discusses the role of the vascular factor in polymorphism of clinical manifestations of tumors and metastases to the brain. It is shown that in 55.4% of cases brain tumors simulated CNS affections. Of these most frequent was the picture of cerebral circulatory disturbances. Mechanisms causing cerebral circulation impairment in various tumors and metastases to the brain are considered. It is found that pathologically changed circulation and angioarchitecture of the tumors may contribute to a wide spectrum of clinical signs typical for vascular brain diseases. The conclusions are based on the analysis of the results obtained with present-day techniques of angio- and neurovisualization and postoperative as well as autopsy examinations of the tumors.