Management and evaluation of localized amyloidosis of the bladder: two case reports

Localized amyloidosis of the bladder is a rare cause of hematuria, which is often confused with bladder cancer. We present case histories of two patients which illustrate the evaluation and management of this entity. The diagnosis is usually made with biopsy and subsequent pathologic examination. Conservative management is attempted initially but must be individualized according to the clinical course of each patient. Transurethral resection will suffice in most instances but occasionally cystectomy is indicated to control local disease.