Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hypothalamic network for thermoregulatory shivering

K Kanosue1, Y H Zhang, M Yanase-Fujiwara

  • 1Department of Physiology, Osaka University Medical School, Japan.

The American Journal of Physiology
|July 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Determination of the Spin and Parity of the Z_{c}(3900).

Physical review letters·2017
Same author

[Effectiveness and safety of rituximab for children with autoimmune diseases of the nervous system].

Zhonghua er ke za zhi = Chinese journal of pediatrics·2017
Same author

Differences in expression of serum protein in patients with psoriasis vulgaris and blood heat syndrome and healthy volunteers.

Cellular and molecular biology (Noisy-le-Grand, France)·2017
Same author

[Correlation between serum uric acid level and acute renal injury after coronary artery bypass grafting].

Zhonghua yi xue za zhi·2017
Same author

[Survey of economic burden of hepatitis B-related diseases in 12 areas in China].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2017
Same author

[Long-term effectiveness of transvaginal high uterosacral ligament suspension].

Zhonghua fu chan ke za zhi·2017
Same journal

Blood coagulation in fish.

The American journal of physiology·2011
Same journal

Renal tubular reabsorption, metabolic utilization and isomeric fractionation of lactic acid in the dog.

The American journal of physiology·2010
Same journal

The inactivation of placental toxin by human serum.

The American journal of physiology·2010
Same journal

Adrenal function following ovariectomy in the rat.

The American journal of physiology·2010
Same journal

Capillary permeability; perfusion of frog and guinea pig hind limbs.

The American journal of physiology·2010
Same journal

Evaluation of protective measures against sunburn.

The American journal of physiology·2010
See all related articles

Unilateral warming of the rat

Area of Science:

  • Neuroscience
  • Physiology
  • Thermoregulation

Background:

  • The preoptic area and anterior hypothalamus (POAH) regulate body temperature.
  • Shivering is a key physiological response to cold, controlled by the POAH.
  • The neural pathways for shivering control, particularly their midline crossing, are not fully understood.

Purpose of the Study:

  • To investigate whether shivering suppression signals cross the midline within or below the POAH.
  • To determine the descending pathways involved in bilateral shivering suppression from unilateral POAH thermal stimulation.

Main Methods:

  • Surgical transection of the POAH (midsagittal) or hypothalamus (coronal) in rats.
  • Unilateral thermal stimulation of the POAH while measuring hind paw shivering.

Related Experiment Videos

  • Comparison of shivering suppression in intact and transected rats.

    • Main Results:

    • Midsagittal POAH transection did not prevent bilateral shivering suppression.
    • Coronal hypothalamic transection on one side abolished shivering suppression from that side but not the other.
    • Transection including the medial forebrain bundle yielded similar results to whole hypothalamic transection.

    Conclusions:

    • Neural signals for shivering control do not appear to be exchanged between the left and right POAH.
    • Efferent signals from the POAH descend via the medial forebrain bundle.
    • These signals cross the midline below the hypothalamus to bilaterally control shivering.