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Multiformity of elongation factor eEF-2 isolated from rat liver cells

A Gajko1, W Gałasiński, A Gindzieński

  • 1Department of General and Organic Chemistry, Institute of Chemistry, Medical Academy, Białystok, Poland.

Biochemical and Biophysical Research Communications
|July 29, 1994
PubMed

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Transcription elongation is a dynamic process that alters depending upon the sequence heterogeneity of the DNA being transcribed. Hence, it is not surprising that the elongation complex's composition also varies along the way while transcribing a gene.
The transcription elongation is regulated via pausing of RNA polymerase on several occasions during transcription. In bacteria, these halts are necessary because the transcription of DNA into mRNA is coupled to the translation of that mRNA into a...