[Basic principles of drug therapy in andrology. Experiences of 40 years andrologic treatment]

Medical treatment of fertility disorders in the male must be based on a definitive diagnostic work-up. Before initiating therapy, all possible endogenous and exogenous injurious factors, including a varicocele and the use of nicotine and a variety of medications, must first be excluded. A further important medical measure is actively involving the patient in the treatment plan, which is of particular importance with respect to the above-mentioned points. Another major role in the management of childless couples is andrological/gynecological cooperation. For the treatment of disorders of morphological quality, androgens are to be given preference, while disorders of motility in the presence of largely normal morphological quality respond well to kallikrein.