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[Experiences with mitomycin C]
A Z Gaspar1, S Orgül, J Flammer
1Universitäts-Augenklinik Basel.
Background:
Recently, encouraging results with the use of Mitomycin C in trabeculectomy have been reported.
Patients:
We used Mitomycin C (0.028%) during trabeculectomy in 72 eyes of 68 patients. Forty-one eyes have already been controlled during 6 months and 19 eyes during 9 months after the surgery.
Results:
The mean intraocular pressure after 6 and 9 months was respectively 13 +/- 8 mm Hg and 13 +/- 10 mm Hg. The difference between these results and the preoperative values (27 +/- 9 mm Hg) were statistically significant after 6 and 9 months (p < 0.001). Despite frequent choroidal detachments (20 eyes), the visual acuity recovered during the follow-up to the preoperative values.
Conclusions:
In patients with uncertain prognosis for the intraocular pressure after trabeculectomy, the intraoperative application of Mitomycin C seems to improve considerably the operative success rate.