Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Liver biopsy bleeding time: an unpredictable event

J F Dillon1, K J Simpson, P C Hayes

  • 1Liver Research Laboratories, Department of Medicine, Royal Infirmary, Edinburgh, Scotland.

Journal of Gastroenterology and Hepatology
|May 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

More than a medication: The lived meaning and value of long-acting injectable buprenorphine.

Drug and alcohol dependence reports·2026
Same author

Volatomics for Diagnosis and Risk Stratification of MASLD: A Proof-Of-Concept Study.

Alimentary pharmacology & therapeutics·2025
Same author

The implementation of a hepatitis C testing service in community pharmacies: I-COPTIC consensus statement.

Public health·2024
Same author

Multimodal decoding of human liver regeneration.

Nature·2024
Same author

Cost-effectiveness of pharmacy-led versus conventionally delivered antiviral treatment for hepatitis C in patients receiving opioid substitution therapy: An economic evaluation alongside a pragmatic cluster randomised trial.

The Journal of infection·2022
Same author

Increased case-finding and uptake of direct-acting antiviral treatment essential for micro-elimination of hepatitis C among people living with HIV: a national record linkage study.

HIV medicine·2020
Same journal

Patient-Level Predictors of Procedural Success in Colon Capsule Endoscopy: A Systematic Review and Meta-Analysis.

Journal of gastroenterology and hepatology·2026
Same journal

Preventive Effect of Helicobacter pylori Treatment on Colorectal Cancer Incidence and Mortality.

Journal of gastroenterology and hepatology·2026
Same journal

Toward the Era of Precision Immunotherapy: The Clinical Landscape and Future Directions of mRNA Vaccines for the Treatment of Hepatocellular Carcinoma.

Journal of gastroenterology and hepatology·2026
Same journal

From Chronic Atrophic Gastritis to Low-Grade Intraepithelial Neoplasia: A Proteomic Study on the Sequential Progression of Gastric Precancerous Lesions.

Journal of gastroenterology and hepatology·2026
Same journal

Resource-Stratified Carbon-Adjusted Quality Indicators for Green Endoscopy.

Journal of gastroenterology and hepatology·2026
Same journal

Five-Year Outcomes and Disease Trajectories in Moderate-to-Severe Ulcerative Colitis: A Korean Multicenter Inception Cohort.

Journal of gastroenterology and hepatology·2026
See all related articles

Liver biopsy bleeding time showed no correlation with platelet count or prothrombin time ratio in 51 patients. Normal coagulation tests do not guarantee absence of bleeding risk after liver biopsy.

Area of Science:

  • Hepatology
  • Surgical Procedures
  • Hematology

Background:

  • Liver biopsy is a common diagnostic procedure.
  • Assessing bleeding risk is crucial before liver biopsy.
  • Coagulation parameters like platelet count and prothrombin time ratio are often used to predict bleeding risk.

Purpose of the Study:

  • To investigate the correlation between liver biopsy bleeding time and pre-procedural coagulation status.
  • To determine if platelet count and prothrombin time ratio predict bleeding after laparoscopic liver biopsy.

Main Methods:

  • Prospective observation of 51 patients undergoing laparoscopic liver biopsy.
  • Measurement of post-biopsy bleeding time.
  • Analysis of correlation with pre-biopsy platelet count and prothrombin time ratio.

Related Experiment Videos

Main Results:

  • No significant correlation was found between liver biopsy bleeding time and platelet count.
  • No significant correlation was observed between liver biopsy bleeding time and prothrombin time ratio.
  • Mild to moderate coagulopathy did not correlate with prolonged bleeding time.

Conclusions:

  • Standard coagulation tests (platelet count, prothrombin time ratio) may not accurately predict bleeding risk after liver biopsy.
  • Hepatologists should remain vigilant for post-biopsy bleeding even with normal coagulation parameters.
  • Further research may be needed to identify better predictors of bleeding after liver biopsy.