[Unusual course of a malignant exophthalmos]

In spite of careful choice of therapy for the individual case, including all the methods used hitherto, such as total thyroidectomy, hypophyseal castration by surgery or irradiation, the prognosis of malignant exophthalmos is very unfavorable. The unusual intense and persistent growth of fatty and connective tissue in the orbit was striking in our patient. The forward thrusting tissue could only be brought to a standstill by X-irradiation of both orbits. The hyperthyroidism itself only showed improvement months later.