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Olfactory neurones expressing distinct odorant receptor subtypes are spatially segregated in the nasal
J Strotmann1, I Wanner, T Helfrich
1University Stuttgart-Hohenheim, Institute of Zoophysiology, Germany.
Cell and Tissue Research
|June 1, 1994
Abstract:
In situ hybridization techniques have been employed to explore the olfactory epithelium of the rat for the distribution of odorant receptor gene transcripts. We demonstrate that olfactory neurone subpopulations expressing distinct receptor subtypes are spatially segregated within the olfactory epithelium. A compartmentalization of the neuroepithelium into distinct expression zone is apparent, cells expressing a specific receptor are randomly distributed within a given zone. Structurally related receptor subtypes share a common distribution pattern.