Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Physical effort-induced changes in immune parameters

L Grazzi1, A Salmaggi, A Dufour

  • 1Department of Neurology, Istituto Neurologico C. Besta, Milano, Italia.

The International Journal of Neuroscience
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Seawater mercury species and phytoplankton biomass drive bioaccumulation in a coastal plankton food web.

Chemosphere·2026
Same author

TFEB inhibition induces melanoma shut-down by blocking the cell cycle and rewiring metabolism.

Cell death & disease·2023
Same author

Multiomics approach to profiling Sertoli cell maturation during development of the spermatogonial stem cell niche.

Molecular human reproduction·2023
Same author

Metabolic transitions define spermatogonial stem cell maturation.

Human reproduction (Oxford, England)·2022
Same author

Integrating melt electrowriting and inkjet bioprinting for engineering structurally organized articular cartilage.

Biomaterials·2022
Same author

MMP8 increases tongue carcinoma cell-cell adhesion and diminishes migration via cleavage of anti-adhesive FXYD5.

Oncogenesis·2021
Same journal

Thoracic paravertebral nerve block combined with general anesthesia for patients undergoing minimally invasive vertebroplasty: effects on pain and lumbar function.

The International journal of neuroscience·2026
Same journal

Recurrence associated IGFBP2 promotes malignant progression and epithelial mesenchymal transition in glioma cells via the AKT mTOR pathway.

The International journal of neuroscience·2026
Same journal

Decreased miR-1305 expression is associated with tumour invasiveness and poor prognosis in glioma patients.

The International journal of neuroscience·2026
Same journal

Astaxanthin alleviates ischemia-reperfusion injury by regulating the JAK2/STAT3 signaling pathway.

The International journal of neuroscience·2026
Same journal

Clinical efficacy of cryopreserved autologous bone flaps versus titanium plates for cranioplasty: a retrospective comparative study.

The International journal of neuroscience·2026
Same journal

Sericin improves diabetic cognitive impairment in rats by inhibiting TXNIP/NLRP3 neuroinflammation through SIRT1.

The International journal of neuroscience·2026
See all related articles

Physical exercise alters immune cell counts and subsets, with norepinephrine levels rising. The spleen does not appear to play a significant role in these exercise-induced immune responses.

Area of Science:

  • Immunology
  • Exercise Physiology
  • Stress Response

Background:

  • Physical stress impacts immune system parameters, influenced by training.
  • Mechanisms are not fully understood, with sympathetic activation and spleen involvement suggested.

Purpose of the Study:

  • To investigate exercise-induced changes in immune parameters.
  • To compare these changes in swimmers, untrained controls, and splenectomized individuals.

Main Methods:

  • A 20-minute cycloergometer test up to 80% maximal heart rate.
  • Measurement of white blood cells (WBC), lymphocyte subsets, plasma catecholamines, and cortisol.
  • Comparison across three subject groups: swimmers, untrained controls, and splenectomized individuals.

Related Experiment Videos

Main Results:

  • Exercise increased WBC and altered percentages of most lymphocyte subsets (NK, CD3+, CD4+, CD8+, CD4/CD8 ratio), excluding DR+ and CD14+ cells.
  • Norepinephrine levels rose post-exercise; epinephrine and cortisol remained unchanged.
  • Splenectomized patients showed similar changes to controls and swimmers.

Conclusions:

  • Physical exertion significantly impacts immune responses.
  • The spleen plays a minimal role in mediating these exercise-induced immune changes.