Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Streaming potential measurements at low ionic concentrations reflect bone microstructure

L A MacGinitie1, K G Seiz, M W Otter

  • 1Orthopaedic Engineering and Research Center, Helen Hayes Hospital, West Haverstraw, New York.

Journal of Biomechanics
|July 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Aramid-epoxy composite internal fixation plates: a pilot study.

Clinical biomechanics (Bristol, Avon)·2013
Same author

On the relationship between streaming potential and strain in an in vivo bone preparation.

Calcified tissue international·2002
Same author

Does bone perfusion/reperfusion initiate bone remodeling and the stress fracture syndrome?

Medical hypotheses·2000
Same author

Effects of electromagnetic fields in experimental fracture repair.

Clinical orthopaedics and related research·1999
Same author

Skeletal cell stresses and bone adaptation.

The American journal of the medical sciences·1998
Same author

Bone streaming potentials and currents depend on anatomical structure and loading orientation.

Journal of biomechanics·1998
Same journal

Influence of iliofemoral ligament laxity on hip joint contact forces during gait.

Journal of biomechanics·2026
Same journal

Associations of sagittal spinal alignment with shear wave velocity, thickness, and echo intensity of muscles attached to the spine and pelvis in healthy women.

Journal of biomechanics·2026
Same journal

The gait lab effect: symmetry restoration strategy after anterior cruciate ligament reconstruction is different in natural environments than the gait laboratory.

Journal of biomechanics·2026
Same journal

Mediolateral trunk control, rather than temporal gait control, is associated with treadmill walking adaptation in healthy older adults.

Journal of biomechanics·2026
Same journal

Examination of participant sex bias in international society of biomechanics conference abstract submissions: patterns across cohorts, countries, and contexts.

Journal of biomechanics·2026
Same journal

Shear wave velocity of biceps femoris and medial gastrocnemius in different positions and intensities: a cross-sectional study in healthy young males.

Journal of biomechanics·2026
See all related articles

Streaming potentials (SPs) generated in bone’s small fluid spaces, less than 200 Angstroms, may inform bone cells about local matrix structure, aiding mechanically driven bone remodeling.

Area of Science:

  • Biophysics
  • Biomaterials Science
  • Cell Biology

Background:

  • Mechanically driven bone remodeling is influenced by streaming potentials (SPs).
  • The fluid spaces generating SPs are crucial for transmitting structural information to bone cells.
  • Understanding these fluid spaces is key to understanding mechanotransduction in bone.

Purpose of the Study:

  • To estimate the mean radii of fluid spaces responsible for generating electrokinetic fields in cortical bone.
  • To determine if these fluid spaces can provide localized structural information to bone cells.

Main Methods:

  • Streaming potential measurements were conducted across cortical bone strips.
  • Experiments utilized varying saline concentrations.
  • A cylindrical pore model was employed to analyze SP data.

Related Experiment Videos

Main Results:

  • A pore radius of less than 200 Angstroms best fit the streaming potential magnitude as a function of saline concentration.
  • This estimated pore size is smaller than previously reported values.
  • The findings suggest SPs are generated in bone microporosity or occluded canaliculi.

Conclusions:

  • Small fluid spaces, such as micropores or occluded canaliculi, generate streaming potentials in bone.
  • Streaming potentials likely provide bone cells with information about local matrix structure.
  • SPs represent a significant pathway for mechanotransduction in bone remodeling.