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Trisomy 18 and trisomy 21 mosaicism in a Down's syndrome patient
I M Thomas1, R Sayee, L Shavanthi
1Department of Anatomy, St John's Medical College, Bangalore, India.
Journal of Medical Genetics
|May 1, 1994
Abstract:
A male child with typical features of Down's syndrome and mosaicism of two trisomic cell lines, trisomy 18 (84%) and trisomy 21 (16%), is reported. Non-disjunction or anaphase lag of chromosomes 18 and 21 could be the cause.