Pediatric pseudotumor cerebri

Journal of Ophthalmic Nursing & Technology
|July 1, 1994
PubMed

Insights

Pseudotumor cerebri, or idiopathic intracranial hypertension, presents with headache and vision changes. Papilledema and elevated intracranial pressure are key signs, with vision loss being the main permanent complication.

Area of Science:

  • Neurology
  • Ophthalmology

Background:

  • Pseudotumor cerebri (PTC), also known as idiopathic intracranial hypertension (IIH), is a neurological disorder.
  • It is characterized by increased intracranial pressure without a clear cause.

Purpose of the Study:

  • To summarize the key signs, symptoms, and complications of pseudotumor cerebri.
  • To highlight the importance of early diagnosis and management.

Main Methods:

  • Review of clinical signs and symptoms associated with PTC.
  • Analysis of diagnostic findings including imaging and cerebrospinal fluid analysis.
  • Identification of potential complications.

Main Results:

  • Common symptoms include headache, papilledema, and abducens nerve palsies causing diplopia.
  • Elevated intracranial pressure with normal brain imaging and cerebrospinal fluid are diagnostic hallmarks.
  • Vision loss (acuity or visual field deficits) is the most serious permanent complication.

Conclusions:

  • Early recognition of pseudotumor cerebri symptoms is crucial for preventing permanent vision loss.
  • Headache is the most frequent presenting symptom, but visual changes require prompt ophthalmological evaluation.

Related Concept Videos

Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
Increased Intracranial Pressure ll: Pathophysiology01:29

Increased Intracranial Pressure ll: Pathophysiology

Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...
Cerebral Edema ll: Pathophysiology01:22

Cerebral Edema ll: Pathophysiology

Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...