Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Hypophyseal gonadotropic function in gout]

O V Siniachenko, E F Barinov, I V Mukhin

    Likars'Ka Sprava
    |January 1, 1994
    PubMed
    Summary

    This study reveals altered pituitary gonadotropin levels in gout patients, with men showing high luteinizing hormone (LH) and women showing low LH and follicle-stimulating hormone (FSH). Hormonal correction in gout is recommended.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Risk factors and mechanisms of acute pyelonephritis development after contact ureterolithotripsy].

    Urologiia (Moscow, Russia : 1999)·2022
    Same author

    [Extracellular matrix remodeling as a risk factor for the progression of cerebrovascular pathology].

    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2022
    Same author

    [Risks of progression of cerebrovascular pathology associated with the activity of the brain purinergic system].

    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2020
    Same author

    The role of systemic inflammation in the pathogenesis of insulin resistance and metabolic syndrome in patients with chronic hepatitis C.

    Terapevticheskii arkhiv·2019
    Same author

    [Activity of α2-adrenergic and PAF receptors of platelets as risk factor of acute pyelonephritis during urolithiasis in eldery women.]

    Advances in gerontology = Uspekhi gerontologii·2019
    Same author

    [Interaction of epinephrine and ADP in regulation of platelet function in chronic cerebral ischemia ].

    Patologicheskaia fiziologiia i eksperimental'naia terapiia·2017

    Area of Science:

    • Endocrinology
    • Rheumatology
    • Urology

    Background:

    • Gout is a metabolic disorder characterized by hyperuricemia and urate crystal deposition.
    • Reproductive health and hormonal balance can be affected in chronic diseases.
    • The role of hypophyseal gonadotropic function in gout pathogenesis requires further elucidation.

    Purpose of the Study:

    • To investigate the gonadotropic function of the hypophysis in patients with gout.
    • To explore potential correlations between gonadotropin levels, sex hormones, and purine metabolism in gout.

    Main Methods:

    • Assessed gonadotropic hormone levels (LH, FSH) in 109 gout patients.
    • Analyzed hormonal profiles in relation to disease severity (joint and kidney involvement).
    • Examined correlations with sex hormones and purine metabolism markers.

    Related Experiment Videos

    Main Results:

    • Elevated luteinizing hormone (LH) levels were observed in male gout patients.
    • Decreased LH and follicle-stimulating hormone (FSH) levels were found in female gout patients.
    • Severe joint and kidney lesions correlated with suppressed FSH secretion.

    Conclusions:

    • Hormonal dysfunction, specifically in gonadotropic function, is present in gout patients.
    • Correction of identified hormonal imbalances may be therapeutically beneficial.
    • Significant correlations exist between gonadotropin levels, sex hormones, and purine metabolism indices in gout.