[Recurrent astrocytoma versus primary astrocytoma: a comparative study of morphological changes of 32 cases]

The pathologic morphological changes of 32 cases of recurrent astrocytoma (RA) and primary astrocytoma were reported. During recurrence, 20 cases (62.5%) of astrocytomas transformed into cases at higher grades. Twelve cases remained at the same grades as primary tumors. Among 21 cases of RA at grades III and IV, 15 cases (71.4%) came from primary astrocytomas, grades I and II. The change from astrocytoma grade I to grade III or IV took time longer than that from grade II to grade III or IV. The recurrent time of astrocytomas with different grades showed no statistical differences. Postoperative radiotherapy/chemotherapy did not play a major role in grading changes and recurrent time.