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Amoebic appendicitis--a rare entity

R Ahmed1, H Shaikh, M Siddiqui

  • 1Department of Pathology, Aga Khan University Medical Centre, Karachi.

JPMA. the Journal of the Pakistan Medical Association
|April 1, 1994
PubMed
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Histopathological examination of removed appendices is crucial. This study identified 13 cases of amoebic appendicitis, highlighting the need for routine histological analysis in appendectomy cases.

Area of Science:

  • General Surgery
  • Pathology
  • Infectious Diseases

Background:

  • Appendectomy is a common surgical procedure.
  • Histopathological examination of all removed appendices is not consistently performed globally.
  • Amoebic appendicitis is a rare but important differential diagnosis.

Purpose of the Study:

  • To determine the incidence of amoebic appendicitis in a series of appendectomy specimens.
  • To compare the clinical presentation of amoebic appendicitis with acute appendicitis.
  • To emphasize the importance of routine histopathological examination of appendices.

Main Methods:

  • Review of 1400 appendectomy specimens received by the department.
  • Histopathological analysis to identify amoebic trophozoites and inflammation patterns.

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  • Serological tests (IHA) and stool examinations to rule out secondary amoebic involvement.

    • Main Results:

    • 13 cases of amoebic appendicitis were identified among 1400 specimens.
    • Clinical presentations of amoebic appendicitis were indistinguishable from acute appendicitis.
    • Histological findings included tissue necrosis and amoebic trophozoites within the appendiceal wall.
    • Tests confirmed primary appendiceal involvement in 8 patients.

    Conclusions:

    • Routine histopathological examination of all appendectomy specimens is recommended.
    • Histological analysis can identify cases of amoebic appendicitis that may be missed clinically.
    • Early diagnosis of amoebic appendicitis can aid in appropriate patient management.