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Sperm morphology and motility in different age populations
I Mladenović1, S Mićić, N Papić
1Institute for the Application of Nuclear Energy, Zemun, Yugoslavia.
Archives of Andrology
|May 1, 1994
Summary
Semen analysis in men over 40 revealed higher rates of abnormal sperm morphology, including head angulation and bent tails. Immature sperm and lower motile sperm concentration were also observed in older men.
Area of Science:
- Andrology
- Reproductive Medicine
- Spermatozoa Morphology
Background:
- Male infertility affects a significant portion of couples seeking reproductive assistance.
- Routine semen analysis is a cornerstone in the etiological investigation of male infertility.
- Age-related changes in semen parameters are increasingly recognized.
Purpose of the Study:
- To investigate the prevalence and types of sperm abnormalities in relation to age.
- To identify specific morphological defects and their association with patient age.
- To analyze variations in andrological parameters across different age groups.
Main Methods:
- Prospective study involving 77 semen specimens from patients presenting with infertility.
- Routine semen analysis including sperm morphology assessment (head and tail abnormalities).
- Evaluation of sperm concentration, motility, and presence of immature forms.
Main Results:
- Abnormal spermatozoa were more prevalent in patients over 40 years of age.
- The most frequent head abnormality was head angulation (94%), and tail abnormality was bent tail (90%).
- Immature spermatozoa were also noted predominantly in patients over 40; higher motile sperm concentration was observed in men up to 26 years old.
Conclusions:
- Advanced paternal age is associated with increased sperm morphological defects and immature spermatozoa.
- Specific abnormalities like head angulation and bent tails are common in older men.
- Significant heterogeneity in andrological parameters exists, underscoring the need for comprehensive evaluation.