Immunological response to glomerular basement membrane and streptococcal antigensin immunized rabbits

Cellular and humoral responses were ivestigated following human glomerular basement membrane a-d streptococcol Type 12 membrane injections in rabbits. Using the leucocyte migration inhibition test and double diffusion in agar gel, cross-reactivity between the antigens was evident, though neither antigen induced significant proteinuria or nephritis in the dosages given.