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Interaction of water-soluble porphyrins with single- and double-stranded polyribonucleotides
C Bustamante1, S Gurrieri, R F Pasternack
1Department of Chemistry, University of Oregon, Eugene 97403.
Biopolymers
|August 1, 1994
Abstract:
CD and uv-visible absorption studies with several tetracationic water-soluble porphyrin derivatives show that some of these species can serve as probes to discriminate between A- and B-conformational forms of single-stranded polynucleotides. It is also observed that these porphyrins can participate in the formation of double helices by forming transient intermediate complexes en-route to duplex formation.