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Leucocyte count: a predictor of early femoropopliteal graft failure
P R Thomas1, M S Quraishy, R Bowyer
1Department of Vascular Surgery, St George's Hospital, London, UK.
Cardiovascular Surgery (London, England)
|August 1, 1993
Insights
Preoperative white cell count predicts early femoropopliteal graft failure. This finding is significant for vascular surgery outcomes, independent of smoking or run-off.
Area of Science:
- Vascular Surgery
- Biomedical Engineering
Background:
- Femoropopliteal reconstructions are crucial for limb salvage.
- Predicting graft failure is essential for improving patient outcomes.
Purpose of the Study:
- To identify predictors of early graft failure in elective femoropopliteal reconstructions.
Main Methods:
- Assessed patency of 90 femoropopliteal reconstructions at 6 months.
- Analyzed preoperative white cell count as a predictor.
Main Results:
- Preoperative white cell count significantly predicted early graft failure (P < 0.0001).
- This predictor was independent of smoking and run-off status.
Conclusions:
- Elevated preoperative white cell count is a key indicator of poor graft patency.
- Clinical assessment should consider white cell count alongside traditional risk factors.
Abstract:
The patency of 90 elective femoropopliteal reconstructions was assessed 6 months after surgery. The preoperative white cell count was found to be a highly significant predictor of early graft failure (P < 0.0001) independent of other previously recognized predictors of occlusion such as smoking and run-off.