Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Infections by ampicillin-resistant enterococci: a case-control study

M Venditti1, C Fimiani, P Baiocchi

  • 1Servizio Aggregato di Consulenze Infettivologiche, Università La Sapienza Roma, Italy.

Journal of Chemotherapy (Florence, Italy)
|April 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

MANIFESTATION OF RADIOPROTECTIVE PROPERTIES IN COPPER COMPLEXES [CU(LCF3)2] AND [СU(ADM)(PPH3)2]PF6.

Georgian medical news·2025
Same author

BLOOD AND CYTOGENETIC MARKERS IN EXPERIMENTAL BURNS AND THEIR TREATMENT WITH [CU(LCF3)2] AND [СU(ADM)(PPH3)2]PF6.

Georgian medical news·2025
Same author

Efficacy of fosfomycin-containing regimens in treating severe infections caused by KPC-producing klebsiella pneumoniae and carbapenem-resistant acinetobacter baumannii in critically ill patients.

International journal of antimicrobial agents·2024
Same author

Clinical effectiveness of cefiderocol for the treatment of bloodstream infections due to carbapenem-resistant Acinetobacter baumannii during the COVID-19 era: a single center, observational study.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2024
Same author

Ceftazidime/avibactam-resistant meropenem-susceptible KPC-producing Klebsiella pneumoniae: Analysis of cases and evaluation of in vitro activity of fosfomycin-containing combinations.

Journal of global antimicrobial resistance·2023
Same author

Effect of ceftazidime/avibactam plus fosfomycin combination on 30 day mortality in patients with bloodstream infections caused by KPC-producing <i>Klebsiella pneumoniae</i>: results from a multicentre retrospective study.

JAC-antimicrobial resistance·2022
Same journal

Eravacycline in sepsis complicated by <i>Clostridioides difficile</i> infection: a brief case series.

Journal of chemotherapy (Florence, Italy)·2026
Same journal

Apatinib combined with capecitabine plus temozolomide versus sunitinib in advanced gastroenteropancreatic neuroendocrine tumours: a propensity score-matched real-world study.

Journal of chemotherapy (Florence, Italy)·2026
Same journal

Pharmacokinetic/pharmacodynamic optimization of antimicrobial therapy in neutropenic sepsis: a comprehensive review.

Journal of chemotherapy (Florence, Italy)·2026
Same journal

Cefiderocol for <i>Stenotrophomonas maltophilia</i> infections: real-world evidence from a multicenter study and a comprehensive literature review.

Journal of chemotherapy (Florence, Italy)·2026
Same journal

Cefiderocol susceptibility in carbapenem-resistant <i>Acinetobacter baumannii</i>, <i>Pseudomonas aeruginosa</i>, and <i>Stenotrophomonas maltophilia</i> isolates: concordance of disk diffusion with the reference method and comparative analysis of CLSI-EUCAST criteria.

Journal of chemotherapy (Florence, Italy)·2026
Same journal

High-dose continuous infusion of piperacillin/tazobactam via elastomeric pump in a pediatric patient with Kartagener syndrome: pharmacokinetic target attainment and clinical outcome.

Journal of chemotherapy (Florence, Italy)·2026
See all related articles

High-level ampicillin-resistant Enterococci (ARE) infections occurred in 20% of hospitalized patients. ARE infections were linked to older patients, longer hospital stays, and prior antibiotic use.

Area of Science:

  • Clinical Microbiology
  • Infectious Diseases
  • Hospital Epidemiology

Background:

  • Enterococcal infections are a significant cause of hospital-acquired infections.
  • High-level ampicillin resistance (ARE) in Enterococcus is a growing concern.
  • Understanding risk factors for ARE is crucial for infection control.

Purpose of the Study:

  • To determine the prevalence of high-level ampicillin-resistant Enterococci (ARE) in hospitalized patients.
  • To identify clinical factors associated with ARE infections compared to ampicillin-susceptible Enterococcus (ASE) infections.

Main Methods:

  • Retrospective case-control study design.
  • Analysis of 83 consecutive enterococcal isolates from patients with documented infections.
  • Comparison of patient demographics, clinical characteristics, and antibiotic resistance profiles.

Related Experiment Videos

Main Results:

  • 17% of enterococcal isolates were identified as ARE, primarily Enterococcus faecium.
  • ARE infections were associated with older patient age and higher in-hospital fatality rates.
  • Prior antibiotic treatment (imipenem, metronidazole) and prolonged hospitalization were more frequent in ARE cases.
  • ARE isolates showed higher resistance rates to imipenem, ciprofloxacin, and streptomycin.

Conclusions:

  • High-level ampicillin resistance is prevalent in hospital-acquired enterococcal infections.
  • ARE infections are associated with increased patient morbidity and mortality.
  • Antibiotic resistance patterns highlight the need for judicious antibiotic use and infection control strategies.