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[Allergic angiitis with granulomatosis: the Churg and Strauss syndrome]
F Lhote1, L Guillevin, P Godeau
1Service de médecine interne, hôpital Delafontaine, Saint-Denis, France.
La Revue De Medecine Interne
|January 1, 1994
Abstract:
Churg-Strauss Syndrome is a disorder characterized by pulmonary and systemic necrotizing vasculitis, extravascular granulomas, and eosinophilia occurring almost exclusively in patients with asthma or a history of allergy. The clinical manifestations most commonly associated with asthma are mononeuritis multiplex, gastrointestinal, cutaneous, cardiac and renal involvement. ANCA are found in 2/3 of the patients with Churg-Strauss Syndrome and are usually p-ANCA. The treatment of Churg-Strauss Syndrome relies on corticosteroids and cyclophosphamide.