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Staphylococcal lower respiratory infection in children

W I Aderele1, K Osinusi, W B Johnson

  • 1Department of Paediatrics+ and Medical Microbiology, University College Hospital, Ibadan, Nigeria.

West African Journal of Medicine
|January 1, 1994
PubMed

Insights

Staphylococcal lower respiratory infections in children often present with patchy consolidation and pleural effusion. Early antibiotic treatment is crucial, especially for severe cases with Staphylococcus aureus, to prevent complications and mortality.

Area of Science:

  • Pediatric Infectious Diseases
  • Pulmonology

Background:

  • Staphylococcal lower respiratory infections pose a significant threat to young children.
  • Understanding the radiological and clinical spectrum is vital for timely diagnosis and management.

Purpose of the Study:

  • To describe the clinical, radiological, and microbiological features of staphylococcal lower respiratory tract infections in children.
  • To identify risk factors for severe disease and mortality.

Main Methods:

  • Prospective study of 31 children aged 1-48 months with staphylococcal lower respiratory infection.
  • Clinical assessment, radiological imaging, and microbiological investigations were performed.

Main Results:

  • Patchy consolidation was the most common radiological finding, followed by pleural effusion.
  • Complications included heart failure and severe anemia; Staphylococcus aureus bacteremia was noted in 62% of children with pleural effusion.
  • Mortality occurred in 9.7% of cases, primarily in malnourished children who did not receive antibiotics.

Conclusions:

  • Staphylococcal lower respiratory infections in children often manifest with consolidation and effusion.
  • Prompt antibiotic therapy, particularly parenteral, is indicated for staphylococcal pleural effusion.
  • Malnutrition and delayed antibiotic treatment are associated with increased mortality.

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