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Serological definition of bovine MHC class II polymorphism in Holstein-Friesians
P R Nilsson1, G M Schreuder, J D'Amaro
1Department of Animal Husbandry, Agricultural University, Wageningen, The Netherlands.
Tissue Antigens
|April 1, 1994
Abstract:
Analysis of the reaction patterns of 57 putative class II MHC alloantisera revealed 18 B-cell serum clusters, named Ds01-Ds18. These clusters were grouped together in such a manner that 17 provisional serological class II haplotypes were defined. Segregation in half-sib families of these class II haplotypes with serologically defined class I and 1D-IEF defined DRB3 types indicated that the 18 clusters identify class II polymorphisms in cattle and can be considered as local specificities.