Histiocytic necrotizing lymphadenitis without granulocytic infiltration (Kikuchi's disease). A case report

Clinical and pathological findings in a case of necrotizing lymphadenitis are described. Histologically the necrotic areas show striking karyorrhexis, absence of polymorphonuclear granulocytes and surrounding zones of large reactive lymphoid cells. The disorder must be carefully distinguished from a lymphoma which it may resemble closely.