[Pharmacological suppression of gestation by beta-2-aminoethylisothiourea (AET) in rats]

One I.P. injection of 2-beta-aminoethylisothiourea (150 or 200 mg/kg) given to rats on day 14 and eventually also on day 18 of gestation induced a maternal death rate ranging from 0 to 50%, together with frequent (1 dose) or systematic (2 doses) foetal resorption. This type of treatment also impairs further reproductive capacity.