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Solid Phase Synthesis of a Functionalized Bis-Peptide Using "Safety Catch" Methodology
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Synthesis, biological activity and conformational study of a somatostatin hexapeptide analogue containing a reduced

N G Delaet1, P Verheyden, B Velkeniers

  • 1Vrije Universiteit Brussel.

Peptide Research
|January 1, 1993
PubMed

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Peptide Bonds02:35

Peptide Bonds

A peptide bond covalently attaches amino acids through a dehydration reaction. One amino acid's carboxyl group and another amino acid's amino group combine, releasing a water molecule. The resulting bond is the peptide bond. The products that such linkages form are peptides. As more amino acids join this growing chain, the resulting chain is a polypeptide. Each polypeptide has a free amino group at one end. This end has the N-terminal, or the amino-terminal, and the other end has a free...