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Disseminated metastatic cutaneous Crohn's disease
S Peltz1, J P Vestey, A Ferguson
1University Department of Dermatology, Royal Infirmary of Edinburgh, Scotland, UK.
Clinical and Experimental Dermatology
|January 1, 1993
Summary
Metastatic cutaneous Crohn's disease is a rare skin condition. This case highlights a widespread presentation in an 18-year-old male, successfully managed with oral prednisolone.
Area of Science:
- Dermatology
- Gastroenterology
- Immunology
Background:
- Metastatic cutaneous Crohn's disease (MCCD) is the rarest skin manifestation of Crohn's disease (CD).
- MCCD involves noncaseating granulomatous skin infiltration distant from the gastrointestinal tract.
- This condition requires careful diagnosis and management due to its rarity and potential for significant morbidity.
Observation:
- An 18-year-old male presented with widespread MCCD.
- The patient had a history of mild oral and anal CD lesions for 2 years.
- Gastrointestinal symptoms were controlled with sulphasalazine prior to skin lesion onset.
Findings:
- The patient's MCCD responded rapidly to oral prednisolone.
- Relapse occurred 6 months after prednisolone withdrawal.
- Low-dose oral prednisolone is currently required for skin lesion control.
- A notable side effect was the exacerbation of acne vulgaris.
Implications:
- This case underscores the importance of recognizing MCCD in CD patients presenting with unusual skin lesions.
- Early diagnosis and appropriate treatment, such as corticosteroids, are crucial for managing MCCD.
- Long-term management may involve low-dose corticosteroids, with potential for side effects like acne exacerbation.