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Persistent acantholytic dermatosis: sex-related differences in clinical presentation?

M Mokni1, S Aractingi, R Grossman

  • 1Clinics for skin diseases, Hôpital Saint-Louis, Paris, France.

Acta Dermato-Venereologica
|February 1, 1993
PubMed
Summary

A chronic papular eruption in a 58-year-old man was diagnosed as persistent acantholytic dermatosis. This distinct condition, characterized by focal acantholytic dyskeratosis, is compared to Grover's disease.

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Area of Science:

  • Dermatology
  • Histopathology

Background:

  • Persistent acantholytic dermatosis is a rare skin condition.
  • It presents as a chronic papular eruption.
  • The condition has been described under various names.

Observation:

  • A 58-year-old man presented with a 10-year history of chronic papular eruption.
  • Histopathological examination revealed focal acantholytic dyskeratosis.

Findings:

  • The case suggests persistent acantholytic dermatosis is a distinct dermatological entity.
  • Focal acantholytic dyskeratosis is the key histopathological finding.
  • The condition shares similarities with transient acantholytic dermatosis (Grover's disease).

Implications:

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  • Understanding persistent acantholytic dermatosis aids in differential diagnosis.
  • Further research may clarify the relationship between persistent and transient acantholytic dermatosis.
  • Sex-related presentations of these conditions warrant further investigation.