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[Zinc and seasonal conjunctivitis]

F Favennec1, A Catros

  • 1Attaché d'allergogie, C.H.U. de Rennes.

Allergie Et Immunologie
|March 1, 1993
PubMed
Summary

Zinc sulfate supplementation significantly improved seasonal conjunctivitis symptoms in a study of 79 patients. This oligo-element addition to antihistamine formulations showed excellent results for allergy relief.

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Area of Science:

  • Ophthalmology
  • Allergology
  • Nutritional Science

Background:

  • Seasonal conjunctivitis is often linked to pollen allergies.
  • Antihistamines are commonly used but may require adjunctive therapies.
  • Zinc is an essential oligo-element with potential anti-inflammatory properties.

Purpose of the Study:

  • To evaluate the efficacy of zinc sulfate as an add-on therapy for seasonal conjunctivitis.
  • To assess symptom improvement in patients receiving zinc sulfate with antihistamines.

Main Methods:

  • A study involving 79 subjects (35 female, 44 male, mean age 23 years) with seasonal conjunctivitis.
  • Subjects had pollen sensitization and were undergoing desensitization.
  • Zinc sulfate was added to a basal formulation containing on-demand AH1 antihistamines.

Main Results:

  • A significant improvement in symptoms was observed.
  • 78% of cases reported very good to excellent outcomes.
  • The addition of zinc sulfate enhanced the efficacy of the basal antihistamine treatment.

Conclusions:

  • Zinc sulfate is a beneficial addition to standard treatments for seasonal allergic conjunctivitis.
  • This oligo-element offers a promising therapeutic option for managing pollen-induced eye allergies.
  • Further research into zinc's role in ocular surface health is warranted.

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