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[Diarrhea]

S Seewald1, C Schmidt, P M Klassen

  • 1Medizinische Poliklinik, Universtität Bonn.

Schweizerische Rundschau Fur Medizin Praxis = Revue Suisse De Medecine Praxis
|August 3, 1993
PubMed
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A man experienced chronic watery diarrhea for years. Collagenous colitis was diagnosed via colonic biopsy after initial evaluations were inconclusive, highlighting its diagnostic challenge.

Area of Science:

  • Gastroenterology
  • Pathology

Background:

  • Chronic watery diarrhea presents a diagnostic challenge, often requiring extensive investigation.
  • Initial endoscopic evaluations may not reveal the underlying cause of persistent gastrointestinal symptoms.

Observation:

  • A 54-year-old male presented with recurrent, severe watery diarrhea (up to 15 stools/day) lasting for years.
  • Previous coloscopy yielded no pathological findings, and symptoms initially resolved before recurring.
  • Persistent and severe symptoms prompted a re-evaluation of the patient's condition.

Findings:

  • Colon biopsy revealed the presence of collagenous colitis, a rare form of microscopic colitis.
  • The characteristic subepithelial collagen band deposition confirmed the diagnosis.

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Implications:

  • This case underscores the importance of colonic biopsies in diagnosing microscopic colitis when gross findings are absent.
  • Accurate diagnosis of collagenous colitis is crucial for appropriate patient management and symptom relief.
  • Further research into the etiology and optimal treatment of collagenous colitis is warranted.