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Oxalosis associated with aluminum bone disease: a new type of mixed renal osteodystrophy
D Krpan1, S Milutinovic, V Nikolic
1Internal Clinic, Saint Spirit Hospital, Zagreb, Croatia.
Abstract:
An 18-year-old man suffering from uremia was hospitalized because of severe skeletal pain and multiple exostoses. The patient had been treated for 5 years by regular hemodialysis; primary oxalosis was the suspected cause of uremia. Transiliac bone biopsy and subsequent histomorphometric analysis of undecalcified bone specimen as well as specific aluminum staining revealed a picture of oxalosis combined with osteomalacia and a marked accumulation of aluminum at the front of mineralization. This combination of histological features of oxalosis and aluminum bone disease suggests a new type of mixed renal osteodystrophy.
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