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Endothelium-derived nitric oxide modulates renal hemodynamics in the developing piglet

M J Solhaug1, M R Wallace, J P Granger

  • 1Department of Pediatric, Eastern Virginia Medical School, Norfolk 23507.

Pediatric Research
|December 1, 1993
PubMed
Summary

Developing piglets have lower renal blood flow and higher renal vascular resistance than adult pigs. Endothelium-derived nitric oxide inhibition significantly impacts renal hemodynamics more in piglets, suggesting its crucial role in development.

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