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Updated: Sep 22, 2026

Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice
Published on: February 18, 2015
[Tissue changes in the oral cavity of children with primary immunodeficiency states]
Abstract:
The examination of 89 children aged 3-14 with diverse forms of primary immunodeficiency (ID) demonstrated that the most intensive progress of caries, mucosal inflammation and the worst oral hygiene occurred in cellular ID, especially in children with chronic generalized skin and mucosal candidiasis. Antibody defects of immunity enhanced caries in dental hard tissues. Phagocytic defects were also associated with dental caries, disorders of oral mucosa, unsatisfactory oral hygiene. Chronic inflammation in children free of ID produced insignificant defects in oral cavity.
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