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Lens-corrected visual field sensitivity and diabetes

M Lutze1, G H Bresnick

  • 1Department of Ophthalmology, University of Wisconsin, Madison.

Investigative Ophthalmology & Visual Science
|February 1, 1994
PubMed
Summary
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Diabetic patients show localized visual field sensitivity losses, particularly in the S-cone system, correlating with retinopathy severity. Overall sensitivity was not significantly reduced, but localized deficits indicate potential early diabetic eye disease.

Area of Science:

  • Ophthalmology
  • Diabetology
  • Visual Neuroscience

Background:

  • Diabetes mellitus is a systemic disease affecting multiple organs, including the eyes.
  • Diabetic retinopathy is a leading cause of vision loss in diabetic patients.
  • Alterations in visual function, such as reduced sensitivity, may precede structural changes in diabetic eye disease.

Purpose of the Study:

  • To investigate peripheral S-cone system and achromatic visual sensitivity in patients with diabetes.
  • To compare visual sensitivity between diabetic patients and age-matched normal controls.
  • To determine the relationship between visual sensitivity deficits and diabetic retinopathy severity.

Main Methods:

  • Perimetric measurements of peripheral S-cone and achromatic sensitivity were performed.

Related Experiment Videos

  • Lens absorption of short-wavelength light was measured and used for correction.
  • Visual field sensitivity was analyzed before and after lens absorption correction.

    • Main Results:

    • Peripheral field-averaged S-cone and achromatic sensitivities were not significantly different between diabetic patients and controls.
    • Localized visual field sensitivity losses were prevalent in diabetic patients, correlating with retinopathy.
    • Field-averaged S-cone sensitivity decreased significantly with increasing retinopathy severity, independent of age and diabetes duration.

    Conclusions:

    • Diabetes can lead to localized S-cone system sensitivity deficits.
    • These localized deficits are associated with the development and severity of diabetic retinopathy.
    • Early detection of visual field abnormalities may aid in managing diabetic eye complications.