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Surface morphology following photorefractive keratectomy
M Campos1, S L Trokel, P J McDonnell
1Doheny Eye Institute, Los Angeles, CA 90033.
Ophthalmic Surgery
|December 1, 1993
Summary
Corneal dehydration significantly roughens the surface after photorefractive keratectomy (PRK). Avoiding dehydration during and after PRK is crucial for maintaining a smooth corneal surface and optimal visual outcomes.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Surface Science
Background:
- Photorefractive keratectomy (PRK) is a common refractive surgery.
- Maintaining corneal surface integrity is vital for successful outcomes.
- The impact of dehydration on corneal morphology post-PRK requires investigation.
Purpose of the Study:
- To evaluate the effects of surface dehydration on corneal morphology.
- To assess these effects before and after photorefractive keratectomy.
- To determine the efficacy of rehydration in mitigating dehydration-induced changes.
Main Methods:
- Porcine corneas were deepithelialized and subjected to six experimental protocols.
- Protocols included dehydration, rehydration, PRK, and combinations thereof.
- Corneal surface smoothness was quantified using an image analysis system.
Main Results:
- Unablated corneas remained smooth after dehydration.
- Post-PRK dehydration led to significant surface roughening and lamellar fragmentation (P=.0001).
- Rehydration partially restored surface smoothness but did not fully reverse the damage.
Conclusions:
- Corneal dehydration during and after PRK adversely affects corneal surface morphology.
- Dehydration causes significant roughening and fragmentation of superficial lamellae.
- Careful avoidance of corneal dehydration is recommended during and after PRK procedures.