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Published on: March 11, 2017
Effect of ethanol on hepatic apolipoprotein B synthesis and secretion in vitro
T W Wang1, C D Byrne, C N Hales
1Department of Clinical Biochemistry, Addenbrookes Hospital, Cambridge, UK.
Biochimica Et Biophysica Acta
|March 3, 1994
Abstract:
The effect of ethanol on hepatic lipoprotein secretion is not fully understood. This study shows that exposure of HepG2 cells to ethanol significantly increases intracellular apolipoprotein B, apo B mRNA and secreted apolipoprotein B. No other agent has been shown to produce such an increase in apolipoprotein B synthesis or apolipoprotein B mRNA levels.
