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[Prolactin adenoma. Hypophysectomy during pregnancy]
La Nouvelle Presse Medicale
|October 11, 1975
Summary
Ovulation induction medications like HMG and HCG can cause prolactin adenomas in women with amenorrhea and galactorrhea. This case highlights the risk of sudden adenoma growth requiring emergency surgery.
Area of Science:
- Reproductive Endocrinology
- Neurosurgery
Background:
- Amenorrhea and galactorrhea can be associated with hyperprolactinemia.
- Hyperprolactinemia is often treated with ovulation induction agents in infertile women.
Observation:
- A case of amenorrhea with galactorrhea was linked to a prolactin adenoma.
- The adenoma developed secondary to ovulation induction therapy (HMG and HCG).
- Pregnancy occurred in the patient.
Findings:
- The prolactin adenoma rapidly progressed, forming a hematoma.
- Emergency surgery was required due to the adenoma's progression and hematoma formation.
Implications:
- This case underscores the potential risks of ovulation induction agents in patients with amenorrhea and galactorrhea.
- Careful consideration of risks versus benefits is crucial when prescribing these agents.