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Breast malignancy in children

D A Rogers1, T E Lobe, B N Rao

  • 1Department of Surgery, St Jude Children's Research Hospital, Memphis, TN 38101.

Journal of Pediatric Surgery
|January 1, 1994
PubMed
Summary
This summary is machine-generated.

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Pediatric breast cancer is rare, presenting as primary, metastatic, or secondary malignancy. Metastatic breast disease in children indicates widespread cancer and carries a very poor prognosis.

Area of Science:

  • Pediatric Oncology
  • Breast Cancer Research
  • Pediatric Malignancies

Background:

  • Breast cancer is uncommon in pediatric patients.
  • Malignancies in pediatric patients can present in the breast as primary, metastatic, or secondary disease.

Purpose of the Study:

  • To analyze the clinical presentation and outcomes of breast malignancies in pediatric patients.
  • To highlight the significance of breast examination in pediatric oncology.

Main Methods:

  • Retrospective review of 18 pediatric patients treated for breast cancer over 25 years.
  • Analysis of patient demographics, primary diagnosis, metastatic sites, and treatment outcomes.

Main Results:

  • 18 pediatric patients (16 female, 2 male) were treated for breast cancer.

Related Experiment Videos

  • Presentations included primary (2), metastatic (13), and secondary (3) malignancies.
  • Metastatic disease to the breast, primarily from rhabdomyosarcoma, was associated with a fatal outcome in all cases.

    • Conclusions:

    • Breast malignancies in children present diversely, including primary, metastatic, and secondary forms.
    • Routine breast examination is crucial for early detection of metastatic disease in pediatric oncology patients.
    • Metastatic breast disease in children signifies disseminated disease and has a grave prognosis.