[Clinico-morphologic correlations in various types of mesangiocapillary glomerulonephritis]

The possibilities of the transformation of one type of mesangio-capillary glomerulonephritis (MCGN) into another one are studied on the basis of light microscopic and ultrastructural examination of 100 renal biopsies, immunohistochemical reactions and clinical data analysis. Apart from the universally adopted I, II, III and IV types of MCGN, a new type is distinguished which occupies an intermediate position between types I and IV. The degree of clinical manifestations in this type correlated with the progression of morphological changes. Thus, lobular glomerulonephritis (GN) is an evolutive form of MCGN. With the progression of MCGN, the enhancement of severe nephritically-hypertensive forms is noted clinically, domination of the maximally active and active nephritic forms.