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[Cranioplasty using cryopreserved autogenous bone]

Y Asano1, Y Ryuke, M Hasuo

  • 1Department of Neurosurgery, Kariya General Hospital, Aichi, Japan.

No to Shinkei = Brain and Nerve
|December 1, 1993
PubMed
Summary
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Cryopreserved autogenous bone is a viable option for cranioplasty after decompression surgery. While most patients achieve bone union, some experience resorption, particularly those with shunts, and infections are manageable.

Area of Science:

  • Neurosurgery
  • Orthopedic Surgery
  • Biomaterials Science

Context:

  • Cranioplasty is frequently performed after external decompression craniotomy.
  • Autogenous bone, preserved via cryopreservation, is a common graft material.
  • Evaluating graft viability and patient outcomes is crucial.

Purpose:

  • To assess the suitability of cryopreserved autogenous bone for cranioplasty.
  • To evaluate histological changes, radiographic outcomes, morphological changes, and infection rates.
  • To determine the appropriateness of the preservation method.

Summary:

  • 110 patients received cranioplasty using cryopreserved autogenous bone.
  • Bone union was observed in most patients, but 15% showed significant bone resorption/atrophy, especially those with ventriculo-peritoneal shunts.

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  • Five patients (4.5%) developed epidural empyema, successfully treated with graft removal and antibiotics.

    • Impact:

    • Cryopreserved autogenous bone cranioplasty is a cost-effective and straightforward procedure.
    • The method demonstrates a low incidence of serious complications.
    • Findings support the use of cryopreserved autogenous bone in specific neurosurgical reconstructions.