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Updated: Aug 6, 2026

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
10:22

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Published on: December 6, 2016

Seizure disorders in children

G L Holmes1

  • 1Clinical Neurophysiology Laboratory, Children's Hospital, Boston, MA 02115.

Current Opinion in Pediatrics
|December 1, 1993
PubMed

Insights

Recent advancements in epilepsy treatment, including new antiepileptic drugs and surgical options, are significantly improving outcomes for children with seizures. These developments offer new hope for managing difficult-to-treat epilepsy in pediatric patients.

Area of Science:

  • Neurology
  • Pediatric Epilepsy
  • Neuroscience

Background:

  • Childhood seizures and epilepsy present significant challenges.
  • The
  • Decade of the Brain
  • has spurred advancements in neurological research.
  • Medical management of pediatric epilepsy has historically faced limitations.

Purpose of the Study:

  • To highlight recent therapeutic advancements in pediatric epilepsy.
  • To discuss the impact of new antiepileptic drugs and epilepsy surgery.
  • To underscore the role of neuroimaging in epilepsy management.

Main Methods:

  • Review of emerging antiepileptic drugs (AEDs).
  • Analysis of the increasing application of epilepsy surgery in children.
  • Evaluation of advancements in neuroimaging techniques for seizure localization.

Main Results:

  • Introduction of three promising new antiepileptic drugs.
  • Several additional AEDs are in clinical trials.
  • Epilepsy surgery is increasingly successful for intractable pediatric seizures.
  • Improved neuroimaging enhances detection and localization of brain anomalies.
  • Combined therapeutic strategies have dramatically improved quality of life for children with epilepsy.

Conclusions:

  • Significant progress has been made in treating childhood epilepsy.
  • New pharmacological and surgical options offer improved management strategies.
  • Advancements in neuroimaging are crucial for precise diagnosis and treatment planning.

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